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Strong concerns raised about diabetes drug risk

November 3, 2008 by  

Avandia has been linked to liver and heart problemsAn advocacy group has called for the Food and Drug Administration to immediately ban the diabetes drug Avandia, due to serious health concerns.

According to Public Citizen, the drug – manufactured by pharmaceutical company Glaxo-SmithKline – can cause liver failure and other life-threatening conditions.

The group has published a statement in Diabetes Care which cites 14 cases of liver failure that can apparently be linked to Avandia. In 12 instances, the condition resulted in death.

In addition to liver toxicity, the group warns that the medication has been linked to an increased risk of heart attacks, heart failure, bone fractures and complications from vision problems.

"The scientific consensus against Avandia is overwhelming," commented Public Citizen’s Dr. Sidney Wolfe.

"The timing of these findings should give the FDA the momentum it needs to act swiftly to prevent further needless deaths and health damage by banning this drug."

In May 2007, the FDA issued an alert about the heart attack risks associated with Avandia, saying that it would continue to assess its potential dangers.ADNFCR-1961-ID-18856655-ADNFCR

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  • Teresa

    Hello, I am reading about sugar and how it feeds cancer. So, if you are diabetic that means your chances of getting cancer in increased? So, that means insulin is a good thing?

    Diabetes is an autoimmune disease as well?

    I am recently on insulin, I think it is causing rapid heart beat or the ACE inhibitor is reacting with the insulin?

    My thyroid scan says I have numerous cysts on it? Does this cause diabetes?

    Does anyone have any help for me? I am having to figure this out as I go with little help from doctor except when I go for three month check up which takes 2.5 hours to see doctor and by then I have forgotten everything.

    Have you heard anything detrimental about Glimepiride? It is third generation drug and now I am on it.

    If anyone knows anything about my comments, I will be glad to read them, I feel so alone with this disease.


  • http://charter howe

    Gail, I am a diabetic type II since 2007 and I was put on glipezide which did a good job of driving my glucose sugar levels down, but it was also causing frequent bouts with hypoglicemia which is a dangerously low blood sugar level of 50 or less as measured with a glucose meter. That particular dose can’t be adjusted because it won’t work well if less is taken. My doctor changed me to Glucophage which eliminated that problem but my blood suger level is about 20 points higher on average, but no hypoglicemia. I still carry glucose candy tablets with me all the time and I buy them at walmart for two bucks a roll. There is a site on line called WEB MD that has a special prescription drugs information section and you can do a search for the answers to Glimepiride. I try to exercise in spite of my disabilities and stay away from high sodium processed food. I eat lots of supermarket frozen steamers, broccoli, asparagus, cauliflower and corn on the cob. High fat foods and too much dairy stuff will make you uncomfortable. Getting a mixture of carbs, protein and a small amount of fats is important every day and small snacks 6 or 7 times a day are better than one big meal. Your right its a lonely disease but you can get lots of mileage out of your body if you take care of it. Medicare will pay for a one time visit to a hospital nutritionist nurse who will teach you over the course of two weeks 2 hour a day, how to eat properly and talks about other lifestyle changes that diabetics need to make. Cancer and heart attacks and such are certainly more possible with a diabetic, but if you take proper care of yourself your going to realize that there is lots of living to do without worrying about getting something worse. A doctor has to write you a prescription for a nutritionist visit but its important to get this information. If you have trouble getting information on line, send me an email and let me know if I can help further. Regards Howe email:


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