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Hope On The Horizon For Alzheimer’s

January 4, 2013 by  

Hope On The Horizon For Alzheimer’s
PHOTOS.COM

A major breakthrough shows much hope for those suffering from Alzheimer’s, a complicated and devastating disease affecting both victim and loved ones.

The research, published in FASEB Journal, was carried out by scientists from the National Institutes of Health using mice diseased with the equivalent of human Alzheimer’s. When a molecule called TFP5 was injected into the mice, their symptoms reversed and memory was restored. Also remarkable is that the injections caused no toxic side effects.

TFP5 was derived from the regulator of a key brain enzyme, called Cdk5. The over activation of Cdk5 is implicated in the formation of plaques and tangles, the major hallmark of Alzheimer’s disease.

“The next step is to find out if this molecule can have the same effects in people, and if not, to find out which molecule will,” said Gerald Weissmann, M.D., editor-in-chief of the FASEB Journal. “Now that we know that we can target the basic molecular defects in Alzheimer’s disease, we can hope for treatments far better — and more specific — than anything we have today.”

“We hope that clinical trial studies in AD patients should yield an extended and a better quality of life as observed in mice upon TFP5 treatment,” said Harish C. Pant, Ph.D., a senior researcher involved in the work from the Laboratory of Neurochemistry at the National Institute of Neurological Disorders at Stroke at the National Institutes of Health in Bethesda, Md. “Therefore, we suggest that TFP5 should be an effective therapeutic compound.”

Kellye Copas

Staff writer Kellye Copas has several years experience writing for the alternative health industry. Her background is in non-profit fundraising, copywriting and direct mail and web marketing.

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  • Robert Smith

    And what happens if TFP5 treatment is acquired from embrionic stem cells?

    Rob

  • Bev

    I imagine there are more than a few Alzheimer patients who would be glad to try anything to get their memory back. My dad has suffered for a very long time and my mother appears to be following in his footsteps. Whoever is doing the research – keep up the good work and go faster.

  • Nancy Meinhardt

    How can I find out if my father can participate in the clinical trial studies?

    • http://www.facebook.com/celeste.l.bailey Celeste Leiala Bailey

      I’d be interested in checking into the clinical studies for my mom too. Can you post information?

  • http://gravatar.com/cbgard Carlucci
  • Shirley Sorrentino

    Coming from a family of nine children where four of my siblings have been diagnosed with Alzheimers I am extremely excited that there may at last be help coming.

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