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Broccoli compound shown to help prevent lung damage in COPD patients

May 2, 2011 by  

Broccoli compound shown to help prevent lung damage in COPD patientsIn addition to being low in calories and high in a variety of nutrients, broccoli may have the added benefit of helping patients with chronic obstructive pulmonary disease (COPD) fight off lung infections, according to researchers at Johns Hopkins University.

The sulforaphane found in the vegetable stimulates production of a molecule known as Nrf2, which helps produce free radical-neutralizing antioxidants in the body.

“This research may help explain the long-established link between diet and lung disease, and raises the potential for new approaches to treatment of this often-devastating disease,” said study co-author Robert Wise.

The authors theorized that Nrf2 may help increase the amount of macrophages in the body, which are molecules that remove bacteria. They tested their hypothesis using sulforaphanes, because the compound has previously been shown to help produce Nfr2.

The sulforaphane treatment helped kill two types of bacteria that affect people with COPD and increased the macrophage’s ability to uptake bacteria by 300 percent.

In a study of mice, the compound was shown to reduce lung inflammation; while in humans, sulforaphane supplements raised blood levels of antioxidants.

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  • William Knaack

    I have C.O.P.D..What compound of Broccoli are you talking about ? I get these infections of the lung every year..The last one was double pneumonia, which put me in breathing ” Hell” this past year..Can you help me? P. S. I live in Wisconsin ( changable weather )

    • Richard Pawley

      Can’t tell you about the broccoli compound but broccoli itself is very healthy, and one sprig raw is equal to a cupful cooked. Equally important to avoid flu and worse is that most Americans don’t get enough Vitamin D-3 and C and minerals. Starting in May I try to get out in shorts and short sleeves for at least half an hour between 11 a.m. and 2 p.m. with NO sun tan lotion or sun screen, to get the Vitamin D-3 I need. I never use ordinary sun lotion but I don’t let myself get sunburned either. When the lowering sun or cold weather makes me stop I take 10,000 IU of Vitamin D-3. I also take a 2 grams of Vitamin C each day, not the anemic amounts that are recommended by those who should know better. I used to take one gram of Vitamin C and 5,400 IU of Vitamin D-3 but I still got a four to five day flu once (have never had a flu shot or not in 50 years) so now I take the amounts I just mentioned. Most Americans are deficient in minerals too and that is why I switched to ancient sea salts like RealSalt and other salts that contain many minerals and are actually good for you, not like the ordinary table or sea salt that many use. I also take a capsule of magnesium each day because 86% of Americans are deficient in it, and it only costs me a dollar a month to take that. If you will do some reading on it, you will be amazed all it can do for you, but most importantly, if you life in a state like Wisconsin you are most likely deficient in Vitamin D-3 and that can surely effect your lungs in a negative way. Hope you have a better year this year. I am assuming of course that you are not a smoker because some studies show that you shouldn’t take extra C until you quite smoking. Lot’s to learn but good health is worth the effort. God bless you.

      • http://?? Joe H.

        Try some vitamin E as well! It’s very god for your circulation and if you are diabetic it helps your body control your levels!!!

  • http://com i41

    Get your vacinations and stay out of high concentrations of people, don’t live in a city. Limit your interactions with people, bet you have more problems durning the colder months when air is dryer.

  • LeRoy Z.

    William, first of all, get a humidifier. I was diagnosed with COPD about two years ago and my humidifier runs 24/7. I have had no lung infections and only one incident[unexplained] of shortness of breath. Also, if you use a concentrator, [I use one at night now], never, ever use it without the water cup installed and operating properly. When I first started using the concentrator, I used it for a couple of nights without the water cup. When used this way, the air you breathe is too dry. I had a couple of pretty bad days coughing until my lungs got rehydrated. Also, keep in mind that cold air is usually dryer. I have to watch myself when I go outside in the winter time [we live near Buffalo, N.Y.] I get winded very quickly at this time of year. Advice about the broccolin will have to come from elsewhere, except I can say I just eat the regular frozen broccoli from the grocery store. I don’t know if it has made a difference or not as I have eaten it all my life. Anyway, I wish you all the best coping with your illness.

    • Al Sieber

      I don’t live around people, and don’t believe in vaccinations, don’t trust them.

      • Al Sieber

        Also, Leroy, used to live in Rochester, N.Y., left there in 1969 after I got out of the service.

    • terri

      Thank you for your information.
      My question is regarding a concentrator you mentioned in your response to the person in Wisconsin.
      Thank you for your input,it is was very helpful to me

      • LeRoy Z.

        Terri, the concentrator I mentioned is oxygen tharapy. My blood oxygen level was dropping at night, so now I wear an oxygen tube at night and it is connected to the oxygen concentrator which runs all night. I don’t know why my levels would drop just at night and not during the daytime [I've got to get better about asking questions when I'm talking to the doctor.] The machine runs so quietly, you don’t even know it’s there. I also have an oxygen tank on hand for times when the lights go out. This equipment is supplied by an outfit calle ‘LinCare’, and is covered by insurance thank God. When we went on vacation recently, they supplied us with a smaller maching that would be easier to transport, but we couldn’t use it because it was not equipped with the water cup, so we just took the bigger machine and managed with it anyway. I hope this helps….if you still have questions, feel free to ask…I’ll answere as best I can. Take care. Sincerely, LeRoy Z.

  • FWO21

    Well, very interesting, but I have read that raw broccoli is not good for someone with hypothyroidism; at least, not till they get their Tsh hormone levels up. What is your opinion on this?


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