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Bone drug may raise risk of esophageal cancer

January 2, 2009 by  

Fosamax linked to cancerFosamax, which is commonly prescribed to treat osteoporosis, may raise a person’s risk of developing cancer of the esophagus, according to an FDA warning.

More research should be done to explore a potential connection between bisphosphonate medications and cancer, the FDA’s Diane Wysowski wrote in a letter published in the New England Journal of Medicine.

Fosamax is manufactured by Merck and is used to increase bone mass among patients who have osteoarthritis.

According to Wysowski, a total of 23 people taking Fosamax in the U.S. have developed esophageal tumors and eight have died since the drug hit the market in 1995. Similar numbers have been noted in Europe and Japan.

Meanwhile, a separate study published in the Journal of the American Dental Association this week linked bisphosphonates to osteonecrosis of the jaw (ONJ).

Those with ONJ suffer from pain, swelling, infection, loose teeth and exposed bone. Dr. Parish Sedghizadeh of the University of Southern California School of Dentistry said that the condition is much more common than was previously thought among people taking drugs similar to Fosamax.

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  • Bob Livingston

    Fosamax, commonly prescribed to treat osteoporosis is not a treatment at all as prescribed. Fosamax does not lay down new bone according to many studies. It is in truth an antii-bone drug.

  • Chuck

    There is an ongoing process in your bones. Old cells die off and are replaced by new ones. These so called "bone drugs" help you to keep the density you have but inhibit the growth of new bone cells. So, eventualy your bones weaken to the point where a simple bump on the coffee table can cause a fracture. This is being seen in Emergency Rooms all over the country and is being traced back to these bone drugs. Doctors get kick-backs from "Big Pharma" for prescribing these drugs just like Flu Shots. Eating right and exercise will increase bone density. Trust me, you will feel better and it is much safer.

  • JD Smith

    When will the people of this planet smartenup. Fixing the BIG PHARMA problem cannot be done at the Congressional level as they are deep in the pockets of BIG PHARMA. A well known fact is that big pharma contributes a very large amount of $$$ not only to the PAC (political action campaine) fund for Congress, Government Agencies i.e. FDA, FTC and others they also fund research and developement for the Heart Assoc., Diabetes Assoc., Cancer Assoc. and others. They require research to develope drugs etc. for treatment of these illnesses and not cures. Think about it. If big pharma would focus on finding cures for these illnesses and discovered cures they would have to close thier doors of thier shops. That is why they supress the information on natural cures via TV, Radio, Newspapers, News Media etc.. They control this media as sponsors. Just look at how many big pharma adds there are on TV, Radio, Newspapers, Mags etc.. JD

  • Surprise

    A similar drug is being tested for treatment of breast cancer. Reports have been coming in for maybe a year linking it to osteonecrosis of the jaw. Now it’s being linked to esophageal cancer? An anti-cancer drug causes cancer? Well, it wouldn’t be the first time!

  • Implants

    This is true, when I started my work in my mouth for dental implants my Dentist told me I couldn’t take these drugs because they would cause infection. Because he told me that, I decided they weren’t good any time. Please check into this before you use these drugs. The price you pay is not worth it. I also have osteoporosis so they say.

  • Kirby Westen

    cheers very much, I must announce that your website is amazing!


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