Cholesterol Drugs Can Deplete CoQ10 and Increase Heart Failure Risk
January 21, 2009 by Bob Livingston
Some 36 million Americans are now on cholesterol (statin) drugs. Everybody is in on the act—the government, the pharmaceuticals and the medical establishment. The public is overwhelmed. Everybody is sold!
My opinion: The cholesterol mania is commerce pure and simple—high cholesterol is a diet problem, not a drug problem.
Statin drugs work by blocking cellular production of cholesterol in the mevalonate pathway (the liver) but statin drugs also block Coenzyme Q10 (CoQ10) production, a vital heart and brain nutrient, in the same pathway.
The good news is that consumption of 100 to 200 mgs per day of CoQ10 will reverse CoQ10 depletion induced by statins. At least one cholesterol drug manufacturing company has admitted to this widespread problem with statin drugs.
There is particular CoQ10 depletion in seniors when statins are taken at higher doses. Doctors are getting more aggressive at prescribing higher and higher dosages of statin drugs with corresponding higher and higher depletion of CoQ10, increasing the likelihood of impairment in heart-muscle function.
If you take a cholesterol-lowering drug, you should take extra CoQ10. It won’t affect the action of the cholesterol drug, but will greatly improve heart function.
CoQ10 is a nutrient, but in practice it is nearly impossible to obtain therapeutic quantities of CoQ10 from the diet—most especially if one is on statin drugs. CoQ10 supplementation will guarantee adequate levels.
In cardiovascular health, CoQ10 is valued by many alternative physicians for helping angina, high blood pressure and congestive heart failure. Symptoms such as fluid retention, shortness of breath, palpitations, sweating, subjective arrhythmia, purple skin color and nighttime urination were checked for improvement. Overall there was significant improved quality of life.
A six-year study at the University of Texas found that sufferers of congestive heart failure who took CoQ10 in addition to their conventional therapy had a 75 percent chance of survival after three years, compared to 25 percent survival rate for those using conventional therapy alone.
- CoQ10 may normalize heart function in mitral valve prolapse patients.
- CoQ10 may help prevent stroke as well as prevent death in people who have had stroke.
- CoQ10 improves blood circulation.
- CoQ10 helps prevent blood clots.
- CoQ10 is a specific for heart function. More is needed for the aging process.
- CoQ10 may improve the heart’s ability to survive and produce energy in hypoxia (limited oxygen) situations such as: High altitudes, clogged arteries, blood clots, angina and high fat content blood.